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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Calciseptine ： ウィキペディア英語版 Calciseptine Calciseptine (CaS) is a natural neurotoxin isolated from the black mamba ''Dendroaspis p. polylepis'' venom. This toxin consists of 60 amino acids with four disulfide bonds. Calciseptine specifically blocks L-type calcium channels, but not other voltage-dependent Ca2+ channels such as N-type and T-type channels.〔() De Weille, J. R., Schweitz, H., Maes, P., Tartar, A. & Lazdunski, M. Proc. Natl. Acad. Sci. USA 88, ''1991'' 2437-2440.〕 ==History== The Black Mamba (Dendroaspis Polylepis) is generally considered to be of the deadliest snakes on the planet, and is responsible for more many fatalities throughout its sub-Saharan Africa range. Without treatment, the bite of a Black Mamba causes a 100% mortality rate. The venom of the Black Mamba consists of more than 28 peptides. One of these peptides is calciseptine. It makes up 2.8% of the venom of the Black Mamba. When first purified, the peptide was called protein E3, which was later changed to calciseptine by Weille et al.〔〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Calciseptine」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.