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Candidiasis : ウィキペディア英語版
Candidiasis

Candidiasis is a fungal infection due to any type of ''Candida'' (a type of yeast). When it affects the mouth, it is commonly called thrush.〔 Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. Other symptoms may include soreness and problems swallowing.〔 When it affects the vagina, it is commonly called a yeast infection.〔 Signs and symptoms include genital itching, burning, and sometimes a white "cottage cheese-like" discharge from the vagina. Less commonly the penis may be affected, resulting in itchiness.〔 Very rarely, the infection may become invasive spreading throughout the body, resulting in fevers along with other symptoms depending on the parts of the body affected.

More than 20 types of ''Candida'' can cause infection with ''Candida albicans'' being the most common.〔 Infections of the mouth are most common among children less than one month old, the elderly, and those with weak immune systems. Conditions that result in a weak immune system include HIV/AIDS, the medications used after organ transplantation, diabetes, and the use of corticosteroids. Other risks include dentures and following antibiotic therapy. Vaginal infections occur more commonly during pregnancy, in those with weak immune systems, and following antibiotic use. Risk for widespread infection includes being in an intensive care unit, following surgery, low birth weight infants, and those with weak immune systems.

Efforts to prevent infections of the mouth include the use of chlorhexidine mouth wash in those with poor immune function and washing out the mouth following the use of inhaled steroids.〔 Little evidence supports probiotics for either prevention or treatment even among those with frequent vaginal infections. For infections of the mouth, treatment with topical clotrimazole or nystatin is usually effective. Oral or intravenous fluconazole, itraconazole, or amphotericin B may be used if these do not work. A number of topical antifungal medications may be used for vaginal infections including clotrimazole. In those with widespread disease, a number of weeks of intravenous amphotericin B is often used. In certain groups at very high risk antifungal medications may be used preventatively.〔

Infections of the mouth occur in about 6% of babies less than a month old. About 20% of those receiving chemotherapy for cancer and 20% of those with AIDS also develop the disease. About three-quarters of women have at least one yeast infection at some time during their lives. Widespread disease is rare except in those who have risk factors. These diseases are also known technically as candidosis, moniliasis, and oidiomycosis.
== Signs and symptoms ==

Signs and symptoms of candidiasis vary depending on the area affected.〔 Most candidal infections result in minimal complications such as redness, itching, and discomfort, though complications may be severe or even fatal if left untreated in certain populations. In immunocompetent persons, candidiasis is usually a very localized infection of the skin or mucosal membranes, including the oral cavity (thrush), the pharynx or esophagus, the gastrointestinal tract, the rectum, anus, perianal/perirectal or ano-rectal area (in men as well as women), the perineum, the urinary bladder, the fingernails or toenails (onychomycosis), and the genitalia (vagina, penis, etc.).
Candidiasis is a very common cause of vaginal irritation, or vaginitis, and can also occur on the male genitals. In immunocompromised patients, ''Candida'' infections can affect the esophagus with the potential of becoming systemic, causing a much more serious condition, a fungemia called candidemia.
Thrush is commonly seen in infants. It is not considered abnormal in infants unless it lasts longer than a few weeks.〔(【引用サイトリンク】 url=http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001650/ )
Infection of the vagina or vulva may cause severe itching, burning, soreness, irritation, and a whitish or whitish-gray cottage cheese-like discharge. These symptoms are also present in the more common bacterial vaginosis. In a 2002 study, only 33% of women who were self-treating for a yeast infection actually had a such an infection, while most had either bacterial vaginosis or a mixed-type infection. Symptoms of infection of the male genitalia (balanitis thrush) include red skin around the head of the penis, swelling, irritation, itchiness and soreness of the head of the penis, thick, lumpy discharge under the foreskin, unpleasant odour, difficulty retracting the foreskin (phimosis), and pain when passing urine or during sex.〔(NHS: Symptoms of thrush in men (balanitis thrush) )〕
Perianal candidiasis can cause pruritis ani. The lesion can be erythematous, papular, or ulcerative in appearance, and it is not considered to be a sexually transmissible disease.
Esophageal candidiasis can cause difficulty swallowing, or less commonly painful swallowing.〔
Abnormal proliferation of the candida in the gut may lead to dysbiosis. While it is not yet clear, this alteration may be the source of symptoms generally described as the irritable bowel syndrome, and other gastrointestinal diseases.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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