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Capsidiol
Capsidiol is a terpenoid compound that accumulates in tobacco ''Nicotiana tabacum'' and chili pepper ''Capsicum annuum'' in response to fungal infection.〔Maldonado-Bonilla LD, Betancourt-Jiménez M,Lozoya-Gloria E (2008) "Local and systemic gene expression of sesquiterpene phytoalexin biosynthetic enzymes in plant leaves". ''European J. Plant Path.'' 121(4), 439-449.〕 Capsidiol is categorized under the broad term of phytoalexin, a class of low molecular weight plant secondary metabolites that are produced during infection.〔Hammerschmidt R. (1999). "Phytoalexins: What have we learned after 60 years?" ''Anni. Rev. Phytopathol''. 37, 285-306.〕 Phytoalexins are also characterized as a part of a two pronged response to infection which involves a short term response consisting of production of free radicals near the site of infection and a long term response involving the production of hormones and an increase in enzymes to biosynthesize phyoalexins such as capsidiol. ==Mechanism of production== Capsidiol is produced in the pepper fruit ''Capsicum annuum'' or tobacco ''Nicotiana tabacum'' after infection by the oomycete water-mold ''Phytophthora capsici''. In pepper or tobacco fields, the fungus is soil-borne and initially infects roots, collars and lower leaves. Sporangia are moved within fields by contact with field equipment, clothing, gloves, tools etc. and initial infections spread zoospores through splashing of water from irrigation or rain.〔Uchida J.Y.; Aragaki M. (1980). "Chemical Stimulation of oospore formation in ''Phytophthoracapsici''". ''Mycologia'' 72, 1103-1108.〕 Initial responses to infection include production of radical oxygen species, including H2O2.〔Arreola-Cortes A.; Castro-Mercado E.; Lozoya-Gloria E.; Garcia-Pineda E. (2007). "Capsidiol production in pepper fruits (''Capsicum annuum'') induced by arachidonic acid is dependent of an oxidative burst". ''Physiol. Mol. Plant Pathol.'' 70(1-3): 69-76.〕 Exogenous treatment with H2O2 alone has been shown to induce capsidiol production.〔 Capsidiol production is then increased in response to radical oxygen species production.
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