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Cassaine
Cassaine is a toxic compound found within the ''Erythrophleum'' genus of trees. This genus has a range from Senegal to Sudan and Kenya in the east, and south to Zimbabwe and Mozambique. Cassaine was first isolated by the G. Dalma group in 1939 from the ''Erythrophleum guinneese'' tree. Since ancient times Cassaine has been used as an ordeal poison by African tribes. It has also been utilized extensively as an arrow poison by the Casamance people of Senegal. == Structure == The structure of cassaine and other alkaloids found within the ''Erythrophleum'' genus are similar to the structure of cardiac glycosides.〔 The structure of Cassaine is shown below. This similarity to cardiac glycosides accounts for the similarity in cardiac activity between Cassaine and compounds such as digitoxin.〔 Generally, the structure of cassaine and other ''Erythrophleum'' derivatives are considered ''N''-alkylaminoethyl esters of tricyclic diterpene acids containing a perhydrophenanthrene skeleton.〔
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