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Catatonia is a state of neurogenic motor immobility and behavioral abnormality manifested by stupor. It was first described in 1874 by Karl Ludwig Kahlbaum, in ''Die Katatonie oder das Spannungsirresein''〔http://web.archive.org/web/20080209213229/http://www.entwicklung-der-psychiatrie.de/seiten/24.1_kahlbaum_die_katatonie.htm, Archived copy (Internet Archive)〕 (''Catatonia or Tension Insanity''). In the ''Diagnostic and Statistical Manual of Mental Disorders'' 5th edition catatonia is not recognized as a separate disorder, but is associated with psychiatric conditions such as schizophrenia (catatonic type), bipolar disorder, post-traumatic stress disorder, depression and other mental disorders, narcolepsy, as well as drug abuse or overdose (or both). It may also be seen in many medical disorders including infections (such as encephalitis), autoimmune disorders, focal neurologic lesions (including strokes), metabolic disturbances, alcohol withdrawal and abrupt or overly rapid benzodiazepine withdrawal. It can be an adverse reaction to prescribed medication. It bears similarity to conditions such as encephalitis lethargica and neuroleptic malignant syndrome. There are a variety of treatments available; benzodiazepines are a first-line treatment strategy. Electro-convulsive therapy is also sometimes used. There is growing evidence for the effectiveness of NMDA antagonists for benzodiazepine resistant catatonia. Antipsychotics are sometimes employed but require caution as they can worsen symptoms and have serious adverse effects.〔 ==Features== Patients with catatonia may experience an extreme loss of motor skill or even constant hyperactive motor activity. Catatonic patients will sometimes hold rigid poses for hours and will ignore any external stimuli. Patients with catatonic excitement can suffer from exhaustion if not treated. Patients may also show stereotyped, repetitive movements. They may show specific types of movement such as waxy flexibility, in which they maintain positions after being placed in them through someone else in which they resist movement in proportion to the force applied by the examiner. They may repeat meaningless phrases or speak only to repeat what the examiner says. While catatonia is only identified as a symptom of schizophrenia in present psychiatric classifications, it is increasingly recognized as a syndrome with many faces. It appears as the Kahlbaum syndrome (motionless catatonia), malignant catatonia (neuroleptic malignant syndrome, toxic serotonin syndrome), and excited forms (delirious mania, catatonic excitement, oneirophrenia).〔Fink M, Taylor MA: CATATONIA: A Clinician's Guide to Diagnosis and Treatment, Cambridge U Press, 2003"〕 It has also been recognized as grafted on to autism spectrum disorders.〔Dhossche D et al.: Catatonia in Autism Spectrum Disorders, Elsevier, Amsterdam, 2006〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Catatonia」の詳細全文を読む スポンサード リンク
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