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・ Chylismia cardiophylla
・ Chylismia claviformis
・ Chylismia heterochroma
・ Chylismiella
・ Chyliński coat of arms
・ Chylnus
・ Chyloderma
・ Chylomicron
・ Chylomicron retention disease
・ Chylothorax
・ Chylowa Huta
・ Chyluria
・ CHYM
・ CHyM – Cetemps Hydrological Model
・ CHYM-FM
Chymase
・ Chymax
・ Chyme
・ Chymical Wedding of Christian Rosenkreutz
・ Chymnayi
・ Chymopapain
・ Chymopapain S
・ Chymophila
・ Chymosin
・ Chymotrypsin
・ Chymotrypsin C
・ Chymotrypsin-C
・ Chymotrypsinogen
・ Chymsydia
・ Chyna


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Chymase : ウィキペディア英語版
Chymase

Chymases (, mast cell protease 1, skeletal muscle protease, skin chymotryptic proteinase, mast cell serine proteinase, skeletal muscle protease) are a family of serine proteases found primarily in mast cells, though also present in basophil granulocytes (e.g. alpha chymase mcpt8). They show broad peptidolytic activity and are involved in a variety of functions. For example, chymases are released by mucosal mast cells upon challenge with parasites and parasite antigens promoting an inflammatory response. Chymases are also known to convert angiotensin I to angiotensin II and thus play a role in hypertension and atherosclerosis.〔Caughey, GH. Mast cell tryptases and chymases in inflammation and host defense. ''Immu Revs'' 2007 (217): 141-154. PMID 17498057〕
Because of its role in inflammation it has been investigated as a target in the treatment of asthma.〔de Garavilla et al. Journal of Biochemistry 2005(280) pp.18001-18007.〕
== References ==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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