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Cln3 : ウィキペディア英語版
Cln3

G1/S-specific cyclin Cln3 is a protein that is encoded by the ''CLN3'' gene. The Cln3 protein is a budding yeast G1 cyclin that controls the timing of ''Start'', the point of commitment to a mitotic cell cycle. It is an upstream regulator of the other G1 cyclins,〔 and it is thought to be the key regulator linking cell growth to cell cycle progression.〔〔 It is a 65 kD, unstable protein;〔 like other cyclins, it functions by binding and activating cyclin-dependent kinase (CDK).〔
==Cln3 in ''Start'' regulation==
Cln3 regulates ''Start'', the point at which budding yeast commit to the G1/S transition and thus a round of mitotic division. It was first identified as a gene controlling this process in the 1980s; research over the past few decades has provided a mechanistic understanding of its function.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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