翻訳と辞書 Words near each other ・ Colca District, Huancayo ・ Colca District, Victor Fajardo ・ Colca River ・ Colcabamba District, Aymaraes ・ Colcabamba District, Huaraz ・ Colcabamba District, Tayacaja ・ Colcamar District ・ Colcannon ・ COLCAP ・ Colcapirhua ・ Colcapirhua Municipality ・ ColcaSac ・ Colcci ・ Colceag ・ Colceag River ・ Colcemid ・ Colcha "K" Municipality ・ Colcha District ・ Colchagua ・ Colchagua Province ・ Colchagua, O'Higgins ・ Colchagua, Quillón, Bío Bío ・ Colchagua, San Rosendo, Bío Bío ・ Colchane ・ Colchani (Potosí) ・ Colchester ・ Colchester (disambiguation) ・ Colchester (electoral district) ・ Colchester (footwear brand) ・ Colchester (provincial electoral district) Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Colcemid ： ウィキペディア英語版 Colcemid Used in cytogenetics, colcemid, also known as demecolcine, is related to colchicine but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed. ==Mechanism of Action == Colcemid is a microtubule-depolymerizing drug like vinblastine. It acts by two distinct mechanisms. At very low concentration it binds to microtubule plus end to suppress microtubule dynamics. Recent study has found at higher concentration colcemid can promote microtubule detachment from microtubule organizing center. Detached microtubules with unprotected minus ends depolymerize with time. Cytotoxicity of the cells seems to correlate better with microtubule detachment. Lower concentrations affect microtubule dynamics and cell migration.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Colcemid」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.