翻訳と辞書
Words near each other
・ Conceição do Castelo
・ Conceição do Coité
・ Conceição do Jacuípe
・ Conceição do Lago-Açu
・ Conceição do Mato Dentro
・ Conceição do Pará
・ Conceição do Rio Verde
・ Conceição do Tocantins
・ Conceição dos Ouros
・ Conceição e Cabanas de Tavira
・ Conceição e Estoi
・ Conceição Ferreira
・ Conceição Geremias
・ Conceição Lima
・ Conatrullus
Conatumumab
・ Conatus
・ Conatus (album)
・ Conaty
・ Conaty Park
・ Conavalla
・ Conaway
・ Conaway Ranch
・ Conaway Run Lake Wildlife Management Area
・ Conaway, California
・ Conaway, Virginia
・ Conax
・ Conayca District
・ Conboy
・ Conboy Lake National Wildlife Refuge


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Conatumumab : ウィキペディア英語版
Conatumumab

Conatumumab (originally AMG 655) is a monoclonal antibody developed for the treatment of cancer. it is a fully human monoclonal agonist antibody directed against the extracellular domain of human TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) receptor 2 (TR-2, death receptor 5) with potential antineoplastic activity. Conatumumab mimics the activity of native TRAIL, binding to and activating TR-2, thereby activating caspase cascades and inducing tumor cell apoptosis. TR-2 is expressed by a variety of solid tumors and cancers of hematopoietic origin.〔(Statement On A Nonproprietary Name Adopted By The USAN Council – Conatumumab ), ''American Medical Association''.〕〔(National Cancer Institute: Definition of conatumomab )〕
The drug was developed by Amgen Inc.
==Clinical trials==
It will be included in the forthcoming I-SPY2 breast cancer trial.〔http://www.reuters.com/article/idUSN1612347120100317 "Breast cancer study aims to speed drugs, cooperation" March 2010〕

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Conatumumab」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.