翻訳と辞書 Words near each other ・ Congdon Street Baptist Church ・ Congdon's Shop ・ Congdonia (butterfly) ・ Congdü ・ Congea ・ Congea chinensis ・ Congea tomentosa ・ Congebec Logistics ・ Congee ・ Congelation ・ Congelation ice ・ Congelin, Western Australia ・ Congener ・ Congener (alcohol) ・ Congener (chemistry) ・ Congenic ・ Congenital absence of the vas deferens ・ Congenital adrenal hyperplasia ・ Congenital adrenal hyperplasia due to 11β-hydroxylase deficiency ・ Congenital adrenal hyperplasia due to 17 alpha-hydroxylase deficiency ・ Congenital adrenal hyperplasia due to 21-hydroxylase deficiency ・ Congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency ・ Congenital afibrinogenemia ・ Congenital amegakaryocytic thrombocytopenia ・ Congenital amputation ・ Congenital anomalies of spine ・ Congenital anomalies of the genitalia ・ Congenital bilateral perisylvian syndrome ・ Congenital cartilaginous rest of the neck ・ Congenital cataract Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Congenic ： ウィキペディア英語版 Congenic In genetics, two organisms that differ in only one locus and a linked segment of chromosome are defined as congenic. Similarly, organisms that are coisogenic differ in one locus only and not in the surrounding chromosome. Unlike congenic organisms, coisogenic organisms cannot be bred and only occur through spontaneous or targeted mutation at the locus. ==Generating congenic strains== Congenic strains are generated in the laboratory by mating two inbred strains (usually rats or mice), and backcrossing the descendants 5-10 generations with one of the original strains, known as the ''recipient'' strain. Typically selection for either phenotype or genotype is performed prior to each backcross generation. In this manner either an interesting phenotype, or a defined chromosomal region assayed by genotype is passed from the ''donor'' strain onto an otherwise uniform ''recipient'' background. Congenic mice/rats can then be compared to the pure recipient strain to determine whether they are phenotypically different if selection was for a genotypic region, or to identify the critical genetic locus, if selection was for a phenotype. Speed congenics can be produced in as little as 5 back cross generations, through the selection at each generation of offspring that not only retain the desired chromosomal fragment, but that also 'lose' the maximum amount of background genetic information from the donor strain. This is also known as 'Marker Assisted' congenics, due to the use of genetic markers, typically microsatellite markers, but now, more commonly, single nucleotide polymorphism markers (SNPs). The process can be further aided by the superovulation of females, to produce many more eggs. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Congenic」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.