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Corynanthine, also known as rauhimbine, is an alkaloid found in the ''Rauwolfia'' and ''Pausinystalia'' (formerly known as ''Corynanthe'') genera of plants. It is one of the two diastereoisomers of yohimbine, the other being rauwolscine. It is also related to ajmalicine. Corynanthine acts as an α1-adrenergic and α2-adrenergic receptor antagonist with approximately 10-fold selectivity for the former site over the latter. This is in contrast to yohimbine and rauwolscine which have around 30-fold higher affinity for α2-adrenergic over α1-adrenergic. As a result, corynanthine is not a stimulant (or an aphrodisiac for that matter), but a depressant, and likely plays a role in the antihypertensive properties of ''Rauwolfia'' extracts. Like yohimbine and rauwolscine, corynanthine has also been shown to possess some activity at serotonin receptors. ==See also== * Ajmalicine * Rauwolscine * Spegatrine * Yohimbine 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Corynanthine」の詳細全文を読む スポンサード リンク
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