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Creatorrhea
Creatorrhea is the abnormal excretion of muscle fibre in feces.〔"(creatorrhea )", The Free Dictionary〕 The term is made from the prefix ''creat-'' or ''creato-'' which comes from Greek ''kreas'' meaning "flesh". The suffix ''-rrhea'' (or ''-rrhoea'') comes from Greek ''-rrhoia'' meaning "flow," hence discharge.
Digestion of food is achieved through a mixture of mechanical and chemical processes. Failure to produce or secrete chemicals known as digestive enzymes can lead to failure digesting or breaking down specific components of ingested food.
Where there is a failure to produce, release, or convert trypsinogen—an inactive enzyme precursor or zymogen—muscle fibres are not properly digested and are therefore released in the feces. Trypsinogen is produced in the pancreas and released into the alimentary canal where it is converted to the active enzyme trypsin.〔Brown, Thomas A. "Rapid Review Physiology." Mosby Elsevier, 1st ed. p. 244〕
Inflammation of the pancreas, or pancreatitis can therefore precipitate this condition,〔''Merck Manual'', (Pancreatitis entry )〕 as can cystic fibrosis〔Gow R, Francis P, Bradbear R, et al., "Comparative study of varying regimes to improve steatorrhea and creatorrhea in cystic fibrosis: effectiveness of an enteric-coated preparation with and without antacids and cimetidine", ''The Lancet'' (1981), 2: pp. 1,071-1,074."〕 which also affects the production of digestive enzymes.
== References ==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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