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Creutzfeldt–Jakob disease ( )〔Merriam-Webster's Collegiate Dictionary〕 or CJD is a degenerative neurological disease that is incurable and invariably fatal.〔 〕 CJD is at times called a human form of mad cow disease (bovine spongiform encephalopathy or BSE). However, given that BSE is believed to be the cause of variant Creutzfeldt–Jakob (vCJD) disease in humans, the two are often confused. CJD is caused by an infectious agent called a prion. Prions are misfolded proteins that replicate by converting their properly folded counterparts, in their host, to the same misfolded structure they possess. CJD causes the brain tissue to degenerate rapidly, and as the disease destroys the brain, the brain develops holes and the texture changes to resemble that of a kitchen sponge. ==Classification== Types of CJD include: *variant (vCJD): :This is thought to be caused by the consumption of food contaminated with prions, which also cause BSE. * sporadic (sCJD): :This accounts for 85% of cases of CJD.〔 * familial (fCJD): :This accounts for the majority of the other 15% cases of CJD.〔 * iatrogenic: :This form of CJD arises from contamination with tissue from an infected person, usually as the result of a medical procedure. Medical procedures that are associated with the spread of this form of CJD include blood transfusion from the infected person, use of human-derived pituitary growth hormones,〔 gonadotropin hormone therapy,〔 and corneal and meningeal transplants.〔(who.int: "Fact sheets no 180: Variant Creutzfeldt-Jakob disease" Feb 2012 ed. )〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Creutzfeldt–Jakob disease」の詳細全文を読む スポンサード リンク
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