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Cuterebriasis is a parasitic disease affecting rodents, lagomorphs (hares, rabbits, pikas), felines and canines. The etiologic agent is the larval development of bot flies within the ''Cuterebra'' or ''Trypoderma'' genera, which occurs obligatorily in rodents and lagomorphs, respectively. Felines and canines serve as accidental hosts, but research suggests only by ''Trypoderma'' spp. Entrance into the body by first instar larva occurs via mucous membranes of natural orifices or open wounds as opposed to direct dermic penetration. ==Clinical Signs== ''Rabbits, Hares & Lagomorphs'' Usually there do not appear to be any clinical signs.〔Companion Animal Parasite Council 2012〕 Subcutaneous cysts, warbles, may present upon larval deposition out of the body at maturation. ''Felines & Canines'' There are three forms in which Cuterebriasis may present:〔Companion Animal Parasite Council 2012〕 * Myasis * Cerebrospinal * Respiratory Myasis involves subcutaneous cyst formation due to 3rd larval instar maturation, occurring ~30 days post-entry into the body.〔Companion Animal Parasite Council 2012〕 Cysts are often found on the face, neck and trunk, but location varies with larval migration within the host. Serous discharge may be observed from these cysts, which are typically 3-5mm in diameter and include a central pore through which the larvae respire. This pore also serves as a means of exit for the larvae, which occurs anywhere between 3 and 8 weeks post-entry.〔James 2010, p. 213.〕 Cerebrospinal cuterebriasis results from larval migration to the brain. This is seen in cats, and is the proposed cause for feline ischemic encephalopathy and a suggestive causative agent of feline idiopathic vestibular disease.〔James 2010, p. 213.〕 Symptoms of this type of presentation include lethargy, seizures, blindness, abnormal vocalization or gait, circling, and abnormal or no reflex responses.〔James 2010, p. 213.〕 When affecting the central nervous system, cats are known to exhibit violent sneezing attacks that can onset weeks prior to manifestation of other clinical signs.〔Moriello 2013〕 Respiratory disease results when larval migration occurs through the trachea, pharynx, diaphragm, or lungs. Cuterebriasis has been increasingly noted as a cause for dyspnea in felines. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Cuterebriasis」の詳細全文を読む スポンサード リンク
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