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・ Cycloramphus granulosus
・ Cycloramphus izecksohni
・ Cycloramphus juimirim
・ Cycloramphus lutzorum
・ Cycloramphus migueli
・ Cycloramphus mirandaribeiroi
・ Cycloramphus ohausi
・ Cycloramphus rhyakonastes
・ Cycloramphus semipalmatus
・ Cycloramphus stejnegeri
・ Cycloramphus valae
・ Cyclorana
・ Cyclorana australis
・ Cyclorana platycephala
・ Cyclorana vagitus
Cyclorphan
・ Cyclorrhapha
・ Cyclos
・ Cyclos (album)
・ Cyclosa
・ Cyclosa conica
・ Cyclosa sierrae
・ Cyclosalpa bakeri
・ Cyclosarin
・ Cycloscala
・ Cycloschizon
・ Cyclosemia
・ Cycloserine
・ Cycloseris
・ Cyclosia


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Cyclorphan : ウィキペディア英語版
Cyclorphan

Cyclorphan is an opioid compound that is a δ-opioid receptor agonist, a κ-opioid receptor agonist, and a μ-opioid receptor antagonist. Chemically, it is a morphinan and is related to levorphanol.〔
It was first synthesized in 1964 by scientists at Research Corporation.〔 (US Patent 3,285,922 )〕〔Varghese V & Hudlicky T. A Short History of the Discovery and Development of Naltrexone and Other Morphine Derivatives. Chapter 6 in Natural Products in Medicinal Chemistry, Volume 60 of Methods and Principles in Medicinal Chemistry. Ed. Stephen Hanessian. John Wiley & Sons, 2013. ISBN 9783527676552〕 In clinical trials, it had relatively long duration, good absorption, and provided strong pain relief but caused symptoms of psychosis, so its development was not continued.〔
==References==




抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Cyclorphan」の詳細全文を読む



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