翻訳と辞書 Words near each other ・ Cytir Mawr ・ Cytisine ・ Cytisophyllum ・ Cytisopsis ・ Cytisus ・ Cytisus hirsutus ・ Cytisus multiflorus ・ Cytisus proliferus ・ Cytisus scoparius ・ Cytisus striatus ・ CYTL1 ・ Cyto's Puzzle Adventure ・ Cyto-Stain ・ Cytoarchitecture ・ Cytocanis ・ Cytochalasin ・ Cytochalasin B ・ Cytochalasin D ・ Cytochalasin E ・ Cytochemistry ・ Cytochrome ・ Cytochrome b ・ Cytochrome b-245 ・ Cytochrome b-245, alpha polypeptide ・ Cytochrome b5 ・ Cytochrome b5 reductase ・ Cytochrome b5, type A ・ Cytochrome b559 ・ Cytochrome b561 ・ Cytochrome b6f complex Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Cytochalasin ： ウィキペディア英語版 Cytochalasin Cytochalasins are fungal metabolites that have the ability to bind to actin filaments and block polymerization and the elongation of actin. As a result of the inhibition of actin polymerization, cytochalasins can change cellular morphology, inhibit cellular processes such as cell division, and even cause cells to undergo apoptosis. Cytochalasins have the ability to permeate cell membranes, prevent cellular translocation and cause cells to enucleate. Cytochalasins can also have an effect on other aspects of biological processes unrelated to actin polymerization. For example, cytochalasin A and cytochalasin B can also inhibit the transport of monosaccharides across the cell membrane,〔 cytochalasin H has been found to regulate plant growth, cytochalasin D inhibits protein synthesis and cytochalasin E prevents angiogenesis. == Binding to actin filaments == Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monomers from the bound end. Once bound, cytochalasins essentially cap the end of the new actin filament. One cytochalasin will bind to one actin filament.〔 Studies done with cytochalasin D (CD) have found that the formation of CD-actin dimers, contain ATP-bound actin. These CD-actin dimers are reduced to CD-actin monomers as a result of ATP hydrolysis. The resulting CD-actin monomer can bind ATP-actin monomer to reform the CD-actin dimer.〔 CD is very effective; only low concentrations (0.2 μM) are needed to prevent membrane ruffling and disrupt treadmilling. The effects of many different cytochalasins on actin filaments were analyzed and higher concentrations (2-20 μM) of CD were found to be needed to remove stress fibers.〔 In contrast, latrunculin inhibits actin filament polymerization by binding to actin monomers. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Cytochalasin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.