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DMPX
DMPX (3,7-Dimethyl-1-propargylxanthine) is a caffeine analog which displays affinity to A2-adenosine receptors, in contrast to the A1 subtype receptors.〔(3,7-Dimethyl-1-propargylxanthine: a potent and selective in vivo antagonist of adenosine analogs. ) Life Sci. 1988;43(21):1671-84. PMID 3193854〕 DMPX had 28× & 15× higher potency than caffeine in blocking peripheral and central NECA-responses. The locomotor stimulation caused by DMPX (ED50 10 μmol/kg) was similarly higher than caffeine.〔 ==References==
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