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DOTA-TATE
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DOTA-TATE : ウィキペディア英語版
DOTA-TATE

DOTA-TATE, DOTATATE or DOTA-octreotate is a substance which, when bound to various radionuclides, has been tested for the treatment and diagnosis of certain types of cancer, mainly neuroendocrine tumours.
==Chemistry and mechanism of action==
DOTA-TATE is an amide of the acid DOTA (top left in the image), which acts as a chelator for a radionuclide, and (Tyr3)-octreotate, a derivative of octreotide. The latter binds to somatostatin receptors, which are found on the cell surfaces of a number of neuroendocrine tumours, and thus directs the radioactivity into the tumour.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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