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Denopamine
Denopamine (INN) is a cardiotonic drug which acts as a Beta-1 adrenergic receptor agonist.〔Ishide T. Denopamine, a selective beta1-receptor agonist and a new coronary vasodilator. ''Current Medical Research and Opinion''. 2002;18(7):407-13. PMID 12487507〕 It is used in the treatment of angina〔Nakajima D, Negoro N, Nakaboh A, Nakakoji T, Hoshiga M, Nariyama J, Ishihara T, Hanafusa T. Effectiveness of low dose denopamine, a beta1-adrenoceptor agonist, in a patient with vasospastic angina refractory to intensive medical treatment. ''International Journal of Cardiology''. 2006 Apr 4;108(2):281-3. PMID 15913812〕 and may also have potential uses in the treatment of congestive heart failure〔Nishio R, Matsumori A, Shioi T, Wang W, Yamada T, Ono K, Sasayama S. Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart. ''Journal of the American College of Cardiology''. 1998 Sep;32(3):808-15. PMID 9741531〕 and for clearing pulmonary oedema.〔Sakuma T, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, Ohya N, Inoue M, Watanabe Y. Beta1-adrenergic agonist is a potent stimulator of alveolar fluid clearance in hyperoxic rat lungs. ''Japanese Journal of Pharmacology''. 2001 Feb;85(2):161-6. PMID 11286398〕
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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