翻訳と辞書 |
Derepression : ウィキペディア英語版 | Derepression In genetics and biochemistry, a repressor gene inhibits the activity of an operator gene. Removal of repression, such as of an operon so that gene transcription occurs or is enhanced, with the net result frequently being elevation of the level of a specific enzyme. This effect is called derepression. ==Derepression of ALA synthase== One example is the effect of drugs on the activity of ALA synthase, an enzyme involved in heme-synthesis. When inducing for example phenobarbital, griseofulvin or hydantoins, the activity of ALA synthase will rise. The cause is a production of cytochrome P450-production, induced by the drugs, consuming heme. When the amount of heme in the liver decreases, it no longer act as a repressor for its synthesis. On the contrary, ALA synthase increases which leads to an increase in heme-production.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Derepression」の詳細全文を読む
スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|