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Des(1-3)IGF-1 : ウィキペディア英語版 | Des(1-3)IGF-1
des(1-3)IGF-1 is a naturally-occurring, endogenous protein, as well as drug, and truncated analogue of insulin-like growth factor 1 (IGF-1). des(1-3)IGF-1 lacks the first three amino acids at the N-terminus of IGF-1 (for a total of 67 amino acids, relative to the 70 of IGF-1). As a result of this difference, it has considerably reduced binding to the insulin-like growth factor-binding proteins (IGFBPs) and enhanced potency (about 10-fold ''in vivo'') relative to IGF-1.〔〔〔〔 The amino acid sequence of des(1-3)IGF-1 is TLCGAELVDA LQFVCGDRGF YFNKPTGYGS SSRRAPQTGI VDECCFRSCD LRRLEMYCAP LKPAKSA.〔 ==See also==
* IGF-1 LR3 * Mecasermin * Mecasermin rinfabate * Insulin-like growth factor 2
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