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|Section2= |Section3= }} Diaziridines are heterocyclic compounds containing two nitrogen atoms in a three-membered ring. They can be considered as strained hydrazines. Due to the ring strain, the nitrogen atoms are configuration stable leading to cis-trans isomers. They are usually synthesized by a method developed by E. Schmitz: A carbonyl compound is treated with ammonia or respectively a primary aliphatic amine and an aminating reagent like hydroxylamine-O-sulfonic acid (HOSA) under slightly basic conditions.〔Synthesis of monocyclic diaziridines and their fused derivatives; N. N. Makhova, V. Y. Petukhova, V. V. Kuznetsov, ''Arkivoc'', 2008(i), 128-152.() 〕 The final step is based on the intramolecular cyclization of an aminal. ==Reactions== * Unsubstituted diaziridines are often directly oxidized (I2/NEt3) to the more stable diazirines. * They can undergo ring expansion reaction with electrophilic reagents like ketenes or isocyanates. * Some derivatives are neurotropically active. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Diaziridine」の詳細全文を読む スポンサード リンク
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