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Dichlorodiphenyldichloroethylene
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Dichlorodiphenyldichloroethylene (DDE) is a chemical compound formed by the loss of hydrogen chloride (dehydrohalogenation) from DDT, of which it is one of the more common breakdown products.〔(ATSDR - Public Health Statement: DDT, DDE, and DDD )〕 Due to DDT’s massive prevalence in society and agriculture during the mid 20th century, DDT and DDE are still widely seen in animal tissue samples.〔(Pesticide Residues in Foods, Dichlorodiphenyltrichloroethane and Dichlorodiphenyldichloroethylene Content in Prepared Foods )〕 DDE is particularly dangerous because it is fat-soluble like other organochlorines, thus it is rarely excreted from the body and concentrations tend to increase throughout life. The major exception is the excretion of DDE in breast milk, which delivers a substantial portion of the mother's DDE burden to the young animal or child.〔(Breast milk excretion Kinetic of b-HCH, pp'DDE and pp'DDT. Bulletin of Environmental Contamination and Toxicology, 2009 Dec;83(6):869-73 )〕 Along with accumulation over an organism's life, this stability leads to bioaccumulation in the environment which amplifies DDE’s negative effects.
==Synthesis==
DDE is created by dehydrohalogenation of DDT. The loss of HCl results in a double bond on the central (previously quaternary) carbon atoms.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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