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・ Dichomeris anomala
・ Dichomeris anticrates
・ Dichomeris antiloxa
・ Dichomeris antisticha
・ Dichomeris antisticta
・ Dichomeris antizella
・ Dichomeris antizyga
・ Dichomeris aomoriensis
・ Dichomeris aphanopa
・ Dichomeris apicispina
・ Dichomeris aplectodes
・ Dichomeris apludella
・ Dichomeris aprica
・ Dichomeris ardelia
・ Dichomeris ardesiella
Dichloroisoprenaline
・ Dichloromethane
・ Dichloromethane (data page)
・ Dichloromethane dehalogenase
・ Dichloromethyl methyl ether
・ Dichloromuconate cycloisomerase
・ Dichloropane
・ Dichlorophen
・ Dichlorophene
・ Dichlorophenol
・ Dichlorophenolindophenol
・ Dichlorophenylphosphine
・ Dichloropropane
・ Dichlorosilane
・ Dichlorotetrakis(dimethylsulfoxide)ruthenium(II)


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Dichloroisoprenaline : ウィキペディア英語版
Dichloroisoprenaline

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Dichloroisoprenaline (DCI), also known as dichloroisoproterenol, was the first beta blocker ever to be developed. It is non-selective for the β1-adrenergic and β2-adrenergic receptors. DCI has low potency and acts as a partial agonist/antagonist at these receptors.
Although DCI was of no clinical value itself, further developments from DCI eventually led to the development of the clinical candidate pronethalol (withdrawn due to carcinogenicity) and subsequently propranolol (the first clinically successful beta blocker).
Dichloroisoprenaline is a racemic mixture of enantiomers.
== References ==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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