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Diethylcarbamazine (DEC, ''N'', ''N''-diethyl-4-methyl-1-piperazine carboxamide) is a synthetic derivative of piperazine used as an anthelmintic drug used in the treatment of filariasis in humans, dogs and cats. Discovery was attributed to Yellapragada Subbarow. DEC is a synthetic organic compound which is highly specific for several parasites. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. ==Medical uses== DEC is indicated for treatment of individual patients with certain filarial diseases. These diseases include: lymphatic filariasis caused by infection with ''Wuchereria bancrofti'', ''Brugia malayi'', or ''Brugia timori''; tropical pulmonary eosinophilia, and loiasis. In cases of onchocerciasis, another common filarial parasite, the drug is not used. This is because of the intense and unbearable itching associated with the dead subcutaneous parasites. DEC continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis. DEC is also used to prevent heartworm in dogs. Now WHO recommends prescribing DEC to patients who are infected with microfilaeria of filarial parasite and also to control transmission of infection in filariasis endemic areas. Contraindications are previous history of heart problems, gastrointestinal problems, and allergy. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Diethylcarbamazine」の詳細全文を読む スポンサード リンク
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