翻訳と辞書 Words near each other ・ Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase ・ Dihydroorotase ・ Dihydroorotate dehydrogenase ・ Dihydroorotate dehydrogenase (fumarate) ・ Dihydroorotate dehydrogenase (quinone) ・ Dihydrophloroglucinol ・ Dihydroprogesterone ・ Dihydropteroate ・ Dihydropteroate synthase ・ Dihydropteroate synthase inhibitor ・ Dihydropyran ・ Dihydropyridine ・ Dihydropyrimidinase ・ Dihydropyrimidine dehydrogenase ・ Dihydropyrimidine dehydrogenase (NADP+) ・ Dihydropyrimidine dehydrogenase deficiency ・ Dihydroquinidine ・ Dihydroquinine ・ Dihydrosanguinarine ・ Dihydrosanguinarine 10-monooxygenase ・ Dihydrostilbenoid ・ Dihydrostreptomycin ・ Dihydrostreptomycin-6-phosphate 3'alpha-kinase ・ Dihydrotachysterol ・ Dihydrotanshinone ・ Dihydrotestosterone ・ Dihydrotetrabenazine ・ Dihydrothiepine ・ Dihydrothymine ・ Dihydrouracil Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Dihydropyrimidine dehydrogenase deficiency ： ウィキペディア英語版 Dihydropyrimidine dehydrogenase deficiency Dihydropyrimidine dehydrogenase deficiency (DPD deficiency) is an autosomal recessive metabolic disorder in which there is absent or significantly decreased activity of dihydropyrimidine dehydrogenase, an enzyme involved in the metabolism of uracil and thymine. Individuals with this condition may develop life-threatening toxicity following exposure to 5-fluorouracil (5-FU), a chemotherapy drug that is used in the treatment of cancer. Beside 5-FU, widely prescribed oral fluoropyrimidine capecitabine (Xeloda) could put DPD-deficient patients at risk of experiencing severe or lethal toxicities as well. == Genetics == DPD deficiency is inherited in an autosomal recessive manner.〔 This means the defective gene responsible for the disorder is located on an autosome, and two copies of the defective gene (one inherited from each parent) are required in order to be born with the disorder. The parents of an individual with an autosomal recessive disorder both carry one copy of the defective gene, but usually do not experience any signs or symptoms of the disorder. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Dihydropyrimidine dehydrogenase deficiency」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.