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Dihydroxyphenylglycine : ウィキペディア英語版 | Dihydroxyphenylglycine
|Section2= |Section3= }} (''S'')-3,5-Dihydroxyphenylglycine or DHPG is a potent agonist of group I metabotropic glutamate receptors (mGluRs) mGluR1 and mGluR5. DHPG was the first agonist shown to be selective for group I mGluRs. Agonist activity is found in only the (''S'')-isomer, and (''S'')-DHPG may be a partial agonist of group I mGluRs.〔 (''S'')-DHPG has been investigated for therapeutic effects in the treatment of neuronal injury (such as those associated with ischemia or hypoxia), cognitive enhancement, and Alzheimer's disease.〔 3,5-Dihydroxyphenylglycine can be isolated from the latex of ''Euphorbia helioscopia''. ==References==
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