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Diphenylcyclopropenone : ウィキペディア英語版 | Diphenylcyclopropenone
|Section2= |Section3= }} Diphenylcyclopropenone (diphencyprone) is a topically administered drug intended for treating alopecia areata and alopecia totalis. Topical immunotherapy using diphenylcyclopropenone may also be an effective treatment option for recalcitrant warts. ==Mechanism of action== Diphenylcyclopropenone acts as a local irritant, triggering a local sensitization. It triggers an immune response that opposes the action of the autoreactive cells that otherwise cause hair loss.〔(Public summary of positive opinion for orphan designation of diphenylcyclopropenone for the treatment of alopecia totalis ), European Medicines Agency. Document Date: London, 23 April 2009. Doc.Ref.:EMEA/COMP/428277/2006〕
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