翻訳と辞書 Words near each other ・ Diphosphene ・ Diphosphenes ・ Diphosphines ・ Diphosphoglycerate ・ Diphosphoglyceric acid ・ Diphosphoinositol-pentakisphosphate kinase ・ Diphosphoinositol-polyphosphate diphosphatase ・ Diphosphomevalonate decarboxylase ・ Diphosphorus ・ Diphosphorus tetraiodide ・ Diphosphorus tetroxide ・ Diphosphotransferase ・ Diphridas ・ Diphros ・ Diphteramoma ・ Diphthamide ・ Diphthera (moth) ・ Diphthera festiva ・ Diphtheria ・ Diphtheria toxin ・ Diphtheria vaccine ・ Diphtheritic stomatitis ・ Diphtherocome ・ Diphtherocome autumnalis ・ Diphtherocome discibrunnea ・ Diphtherocome pallida ・ Diphtherocome pulchra ・ Diphtheroglyphus ・ Diphtherophorina ・ Diphtheroptila Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Diphthamide ： ウィキペディア英語版 Diphthamide |Section2= |Section3= }} Diphthamide is a modified histidine amino acid found in eukaryotic elongation factor 2 (eEF-2). It is usually found at position H715 in mammalian eEF2 (H699 in yeast). This residue is modified by the protein encoded by the DPH1 (OVCA1) gene. Dph1 knockout mice are inviable while heterozygotes develop diverse types of carcinomas and sarcomas. In humans, DH1 is frequently found mutated in ovarian cancer. Loss of heterozygosity has taken place in 50% of benign tumours, and 90% of end-stage ovarian tumours. It is ADP-ribosylated by diphtheria toxin, hence the name, which renders the elongation factor inactive. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Diphthamide」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.