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Dock10
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Dock10 : ウィキペディア英語版
Dock10

Dock10 (Dedicator of cytokinesis), also known as Zizimin3, is a large (~240 kDa) protein involved in intracellular signalling networks.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55619 )〕 It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors, which function as activators of small G proteins.
==Discovery==
Dock10 was identified via bioinformatic approaches as one of a family of evolutionarily conserved proteins (the DOCK family) that share significant sequence homology. Dock10 is expressed in peripheral blood leukocytes as well as in the brain, spleen, lung and thymus.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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