翻訳と辞書
Words near each other
・ Dock Square (Boston)
・ Dock Street Brewing Company
・ Dock Street Dam
・ Dock Street Theatre
・ Dock Sud
・ Dock Tarn
・ Dock Walloper
・ Dock Walsh
・ Dock warrant
・ Dock Work Convention, 1973
・ Dock, Wharf, Riverside and General Labourers' Union
・ Dock10
・ Dock11
・ Dock180
・ Dock2
Dock3
・ Dock4
・ Dock4-Ex49
・ Dock5
・ Dock6
・ Dock7
・ Dock8
・ DOCK8 deficiency
・ Dock9
・ Dockage
・ Dockanema
・ Dockapps
・ Dockendorf
・ Dockendorff Group
・ Dockenfield


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Dock3 : ウィキペディア英語版
Dock3

Dock3 (Dedicator of cytokinesis 3), also known as MOCA (modifier of cell adhesion) and PBP (presenilin-binding protein), is a large (~180 kDa) protein involved in intracellular signalling networks.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1795 )〕 It is a member of the DOCK-B subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock3 specifically activates the small G protein Rac.
==Discovery==
Dock3 was originally discovered in a screen for proteins that bind presenilin (a transmembrane protein which is mutated in early onset Alzheimer's disease). Dock3 is specifically expressed in neurones (primarily in the cerebral cortex and hippocampus).

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Dock3」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.