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Dorzolamide
Dorzolamide (trade name Trusopt) is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour.〔(Dorzolamide ) at Drugs.com. Revised: 12/2011〕 It is administered as a topical ophthalmic in the form of a 2% solution.〔 ==History== This drug, developed by Merck, was the first drug in human therapy (market introduction 1995) which resulted from structure-based drug design. It was developed to circumvent the systemic side effects of acetazolamide which has to be taken orally.
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