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Carbidopa/levodopa
Carbidopa/levodopa, also known as levocarb and co-careldopa, is the combination of the two medications carbidopa and levodopa.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/levodopa-carbidopa.html )〕 It is primarily used to manage the symptoms of Parkinson's disease but does not change the course of the disease. It is taken by mouth.〔 It can take two to three weeks of treatment before benefits are seen.〔 Each dose then begins working in about ten minutes with a duration of effect of about five hours.
Common side effects include movement problems and nausea.〔 More serious side effects include depression, low blood pressure with standing, sudden onset of sleepiness, psychosis, and the desire to gamble.〔〔 Carbidopa prevents the breakdown of levodopa outside of the brain. In the brain levodopa is broken down into dopamine by which it has its effects.〔
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is available as a generic medication and is moderately expensive. Globally the wholesale price of the medication is about 1.80 to 3.00 USD a month.〔(【引用サイトリンク】url=http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=LVC125T&s_year=2014&year=2014&str=100%2B25%20mg&desc=Levodopa%2BCarbidopa&pack=new&frm=TAB-CAP&rte=PO&class_code2=09%2E&supplement=&class_name=%2809%2E%29Antiparkinsonism%20medicines%3Cbr%3E )〕 In the United States a months supply is about 50 to 150 USD.〔
==Medical uses==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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