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Haplogroup E-V38
In human genetics, Haplogroup E-V38 is a human Y-chromosome DNA haplogroup. It is the phylogenetic term for the series of unique sequence variants on the human Y-chromosome. It is often found in African males and their descendants and is heritably passed in lineage from father to son. Geneticists study these variants in populations to find the evolutionary lineage to a common male human ancestor. It can also be referred to in phylogenetic nomenclature by names such as E1b1a (although the exact definition of phylogenetic names can vary over time).
E-V38 has two basal branches, E-M329 and E-M2, the former is almost exclusively found in Ethiopia. The E-M2 branches are the predominant lineage in Western Africa, Central Africa, Southern Africa, and the southern parts of Eastern Africa. E-M2 has several subclades, however many members are included in either E-L485 or E-U175.
==Origins==
The discovery of two SNPs (V38 and V100) by Trombetta et al. (2011) significantly redefined the E-V38 phylogenetic tree. This led the authors to suggest that E-V38 may have originated in East Africa. V38 joins the West African-affiliated E-M2 and the northern East African-affiliated E-M329 with an earlier common ancestor who, like E-P2, may have also originated in East Africa. It is possible that soon after the evolution of E-V38, trans-Saharan migrants carried the E-V38 marker to Northern Africa and Central Africa and/or West Africa where the more common E-M2 marker later arose and became prolific within the last 20,000-30,000 years.
The downstreams SNP E-M180 possibly originated on the moist south-central Saharan savannah/grassland of northern West Africa during the early Holocene period. Much of the population that carried E-M2 retreated to southern West Africa with the drying of the Sahara. These later people migrated from Southeastern Nigeria and Cameroon ~8.0 kya to Central Africa, East Africa, and Southern Africa causing or following the Bantu expansion. According to Wood et al. (2005) and Rosa et al. (2007), such population movements from West Africa changed the pre-existing population Y chromosomal diversity in Western, Central, Southern and southern East Africa, replacing the previous haplogroups frequencies in these areas with the now dominant E1b1a1 lineages. Traces of earlier inhabitants, however, can be observed today in these regions via the presence of the Y DNA haplogroups A1a, A1b, A2, A3, and B-M60 that are common in certain populations, such as the Mbuti and Khoisan.〔
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