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・ Eierland Lighthouse
・ Eierpunsch
・ Eiersberg
・ Eierschecke
・ EIES
・ EIF
・ EIF-2 kinase
・ EIF-W2 protein domain
・ EIF1
・ EIF1AX
・ EIF1AY
・ EIF1B
・ EIF2
・ EIF2A
・ EIF2AK1
EIF2AK3
・ EIF2AK4
・ EIF2B
・ EIF2B1
・ EIF2B2
・ EIF2B3
・ EIF2B4
・ EIF2B5
・ EIF2C1
・ EIF2C2
・ EIF2S1
・ EIF2S2
・ EIF2S3
・ EIF3A
・ EIF3B


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EIF2AK3 : ウィキペディア英語版
EIF2AK3

Eukaryotic translation initiation factor 2-alpha kinase 3, also known as PRKR-like endoplasmic reticulum kinase or protein kinase R (PKR)-like endoplasmic reticulum kinase, is an enzyme that in humans is encoded by the ''EIF2AK3'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9451 )
== Function ==

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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