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・ EIF3S6
・ EIF4A
・ EIF4A1
・ EIF4A2
・ EIF4A3
・ EIF4B
・ EIF4E
・ EIF4E1B
・ EIF4E2
・ EIF4E3
・ EIF4EBP1
・ EIF4EBP2
・ EIF4EBP3
・ EIF4ENIF1
・ EIF4G
EIF4G2
・ EIF4G3
・ EIF4H
・ EIF5
・ EIF5A
・ EIF5A2
・ EIF5AP1
・ EIF5B
・ EIF6
・ Eifa (Schwalm)
・ Eifan Saadoun Al Issawi
・ Eifel
・ Eifel Aqueduct
・ Eifel Formation
・ Eifel hotspot


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EIF4G2 : ウィキペディア英語版
EIF4G2

Eukaryotic translation initiation factor 4 gamma 2 (also called p97, NAT1, and DAP-5) is a protein that in humans is encoded by the ''EIF4G2'' gene.
== Function ==

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1982 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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