翻訳と辞書 Words near each other ・ Elbert Howard ・ Elbert Hubbard ・ Elbert K. Fretwell ・ Elbert Kimbrough ・ Elbert L. Carpenter House ・ Elbert L. Kinser ・ Elbert L. Lampson ・ Elbert Lee Trinkle ・ Elbert Lowder ・ Elbert Luther Little ・ Elbert Mack ・ Elbert N. Carvel ・ Elazığ Province ・ Elazığspor ・ Elb Adress ・ ELB-139 ・ Elba ・ Elba (disambiguation) ・ Elba (village), New York ・ Elba City Schools ・ Elba DOC ・ Elba Esther Gordillo ・ Elba Fahsbender ・ Elba Guerrero ・ Elba Island ・ Elba Lightfoot ・ Elba Ramalho ・ Elba Rashani ・ Elba Rosa Rodríguez-Fuentes ・ Elba Soccarras Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ELB-139 ： ウィキペディア英語版 ELB-139 ELB-139 (LS-191,811) is an anxiolytic drug with a novel chemical structure, which is used in scientific research. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic. ELB-139 is a subtype-selective partial agonist at GABAA receptors, with highest affinity for the α3 subtype, but highest efficacy at α1 and α2. It has primarily anxiolytic and anticonvulsant effects, but produces little sedative effects or ataxia, and has also been demonstrated in rats to increase serotonin levels in the striatum and prefrontal cortex, without affecting dopamine levels. It has been proposed as a possible candidate for a novel non-sedating anxiolytic or anticonvulsant drug for use in humans The sponsor elbion AG registered a clinical trial in (ClinicalTrials.gov ) for the treatment of anxiety associated with panic disorder but the results have not been reported. It was developed by Arzeitmittelwerk Dresden in the 1990s.〔US Patent 5869481 Anticonvulsive 1-ar(alk)ylimidazolin-2-ones and process for making〕 == References == 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ELB-139」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.