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ENO3
Enolase 3 (ENO3), more commonly known as beta-enolase (ENO-β), is an enzyme that in humans is encoded by the ''ENO3'' gene. This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.(by RefSeq, Jul 2010 )〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/gene/2027 )〕 == Structure == ENO3 is one of three enolase isoforms, the other two being ENO1 (ENO-α) and ENO2 (ENO-γ).〔〔 Each isoform is a protein subunit that can form hetero- or homodimers of the following combinations: αα, αβ, αγ, ββ, and γγ.〔〔〔
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