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EPHA3 : ウィキペディア英語版
EPH receptor A3

EPH receptor A3 (ephrin type-A receptor 3) is a protein that in humans is encoded by the ''EPHA3'' gene.
== Function ==

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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