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ESHAP ESHAP is an acronym for relatively intensive chemotherapy regimen that is used for salvage therapy in relapsed or refractory lymphomas and Hodgkin disease. In combination with monoclonal antibody Rituximab it is called R-ESHAP or ESHAP-R.〔(ESHAP--an effective chemotherapy regimen in refractory and relapsing lymphoma: a 4-year follow-up study. )〕 ()-ESHAP consists of: # (R)ituximab, an anti-CD20-directed monoclonal antibody that kills both normal and malignant B-lymphocytes # (E)toposide, an epipodofyllotoxin topoisomerase inhibitor # (S)olu-Medrol - Methylprednisolone, which is a glucocorticoid that can lyse lymphocytes # (H)igh-dose (A)ra-C - cytarabine # (P)latinol - Cisplatin, an platinum-based antineoplastic agent with an alkylating mechanism; == Dosing regimen ==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「ESHAP」の詳細全文を読む
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