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・ Ectabola
・ Ectaco
・ Ectaco jetBook
・ Ectadiosoma
・ Ectaesthesius
・ Ectaga
・ Ectaga canescens
・ Ectaga garcia
・ Ectaga lenta
・ Ectaga lictor
・ Ectaga promeces
・ Ectasia
・ Ectasian
・ Ectasjapyx
・ Ectatina irrorata
Ectatomin
・ Ectatomma
・ Ectatomma parasiticum
・ Ectatomma ruidum
・ Ectatomma tuberculatum
・ Ectatomminae
・ Ectatosia
・ Ectatosia invitticollis
・ Ectatosia maculosa
・ Ectatosia moorei
・ Ectatosia sumatrensis
・ ECTC
・ Ecteinascidia
・ Ecteinascidia turbinata
・ Ecteinomyces


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Ectatomin : ウィキペディア英語版
Ectatomin

In molecular biology, ectatomin is a toxin from the venom of the ant ''Ectatomma tuberculatum''. Ectatomin can efficiently insert into the plasma membrane, where it can form channels. Ectatomin was shown to inhibit L-type calcium currents in isolated rat cardiac myocytes. In these cells, ectatomin induces a gradual, irreversible increase in ion leakage across the membrane, which can lead to cell death.
Ectatomin is composed of two subunits, A and B, which are homologous. The structure of ectatomin reveals that each subunit consists of two alpha helices with a connecting hinge region, which form a hairpin structure that is stabilised by disulphide bridges. A disulphide bridge between the hinge regions of the two subunits links the heterodimer together, forming a closed bundle of four helices with a left-handed twist.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Ectatomin」の詳細全文を読む



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