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An ejectosome is a cellular organelle responsible for ejecting their contents from the cell. Two unrelated types of ejectosomes are described in the literature: # Cryptomonads have two types of characteristic ejectisomes known as extrusomes. # Intracellular pathogens, such as ''Mycobacterium tuberculosis'', escape from their host cells using an actin-based structure, also called an ejectosome. Cryptomonad ejectosomes contain two connected spiral ribbon-like structures, held under tension.〔(Cryptophyte With Ejectosome Electron Micrograph. )〕 If the cells are irritated either by mechanical, chemical or light stress, they discharge, propelling the cell in a zig-zag course away from the disturbance. Large ejectisomes, visible under the light microscope, are associated with the pocket; smaller ones occur elsewhere on the cell.〔(Cryptomonads = Goniomonas + plastid-containing cryptophytes. )〕 Mycobacteria are ejected from host cells through the action of an actin-based ejectosome. This escape mechanism requires a cytoskeleton regulator from the host plus an intact mycobacterial ESX-1 secretion system. Ejectosomes apparently exert a contractile force, forming a tight septum around the bacteria. Ejection of the bacteria occurs without host cell lysis.〔(Hagedorn, M. et al. Infection by Tubercular Mycobacteria Is Spread by Nonlytic Ejection from Their Amoeba Hosts. Science 27 March 2009: Vol. 323. no. 5922, pp. 1729 - 1733. )〕 ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Ejectosome」の詳細全文を読む スポンサード リンク
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