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Eluxadoline
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Eluxadoline : ウィキペディア英語版
Eluxadoline

Eluxadoline (INN, USAN) (brand name Viberzi; former developmental code name JNJ-27018966) is a novel, orally-active drug approved for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D). It was approved for use by the United States Food and Drug Administration on May 27, 2015. The drug originated from Janssen Pharmaceutica and was developed by Actavis.
==Mechanism of action==
Eluxadoline is a μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist that acts locally in the enteric nervous system, possibly decreasing adverse effects on the central nervous system.


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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