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Enzastaurin
|Section2= |Section3= }} Enzastaurin is a synthetic bisindolylmaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply, preventing growth. In 2013 it failed a phase III clinical trial for lymphoma.〔(Lilly Halts Development of Lymphoma Drug After Phase III Failure )〕 ==References==
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