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Eosinophilia is a condition in which the eosinophil count in the peripheral blood exceeds 4.5×108/L (450/μl). Eosinophils usually account for less than 7% of the circulating leukocytes.〔(【引用サイトリンク】 title=Eosinophilic Disorders )〕 A marked increase in non-blood tissue eosinophil count noticed upon histopathologic examination is diagnostic for tissue eosinophilia.〔 Several causes are known, with the most common being some form of allergic reaction or parasitic infection. Diagnosis of eosinophilia is via a complete blood count (CBC), but diagnostic procedures directed at the underlying cause vary depending on the suspected condition(s). An absolute eosinophil count is not generally needed if the CBC shows marked eosinophilia.〔 The location of the causal factor can be used to classify eosinophilia into two general types: extrinsic, in which the factor lies outside of the eosinophil cell lineage; and intrinsic eosinophilia, which denotes etiologies within the eosiniphil cell line.〔 Specific treatments are dictated by the causative condition, though in idiopathic eosinophilia, the disease may be controlled with corticosteroids. Eosinophilia is not a disorder, unless it is idiopathic.〔 ==Causes== Eosinophilia can be idiopathic (primary) or, more commonly, secondary to another disease.〔〔 In the Western World, allergic or atopic diseases are the most common causes, especially those of the respiratory or integumentary systems. In the developing world, parasites are the most common cause. A parasitic infection of nearly any bodily tissue can cause eosinophilia. Diseases that feature eosinophilia as a sign include the following: *Allergic disorders * *Asthma * *Hay fever〔 * *Drug allergies〔 * *Allergic skin diseases〔 * * *Pemphigus〔 * * *Dermatitis herpetiformis *Eosinophilic esophagitis〔http://www.acaai.org/allergist/allergies/Types/food-allergies/types/Pages/eosinophilic-esophagitis.aspx〕 *Eosinophilic gastroenteritis *Parasitic infections〔 *Addison's disease *Some forms of malignancy * *Acute lymphoblastic leukemia * *Chronic myelogenous leukemia * *Eosinophilic leukemia * *Hodgkin lymphoma〔 * *Some forms of non-Hodgkin lymphoma〔 *Systemic autoimmune diseases〔 (e.g., SLE, idiopathic eosinophilic synovitis) *Systemic mastocytosis *Some forms of vasculitis〔 (e.g., Churg-Strauss syndrome) *Cholesterol embolism (transiently)〔 * Coccidioidomycosis (Valley fever), a fungal disease prominent in the US Southwest. * Human immunodeficiency virus infection *Interstitial nephropathy *Hyperimmunoglobulin E syndrome, an immune disorder characterized by high levels of serum IgE *Idiopathic hypereosinophilic syndrome. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Eosinophilia」の詳細全文を読む スポンサード リンク
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