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Ephenidine : ウィキペディア英語版
Ephenidine

Ephenidine (also known as NEDPA and EPE) is a dissociative anesthetic that has been sold online as a designer drug. It is illegal in some countries as a structural isomer of the banned opioid drug lefetamine, but has been sold in countries where it is not yet banned.
Ephenidine and related diarylethylamines have been studied in vitro as treatments for neurotoxic injuries, and are antagonists of the NMDA receptor.〔(【引用サイトリンク】 title=Patent EP 0346791 B1 - 1,2-diarylethylamines for treatment of neurotoxic injury. )
==Metabolism==
Ephenidine undergoes the following metabolic steps: N-oxidation, N-dealkylation, mono- and bis-hydroxylation of the benzene ring, and hydroxylation of the phenyl ring only after N-dealkylation. The dihydroxy metabolites were conjugated by methylation of one hydroxy group, and hydroxy metabolites by glucuronidation or sulfation.〔

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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