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Erythroferrone : ウィキペディア英語版 | Erythroferrone
Erythroferrone is a protein hormone, abbreviated as ERFE, encoded in humans by the ''FAM132B'' gene. Erythroferrone is produced by erythroblasts, inhibits the action of hepcidin, and so increases the amount of iron available for hemoglobin synthesis.〔 〕 == Discovery == It was identified in 2014 in mice where the transcript was found in bone marrow, encoded by the mouse ''Fam132b'' gene.〔 The homologous gene in humans is ''FAM132B'' and the sequence is conserved in other species. The protein is synthesized by erythroblasts and secreted.〔 This sequence had previously been found expressed in mouse skeletal muscle, called myonectin (CTRP15), and linked to lipid homeostasis.〔 〕
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Erythroferrone」の詳細全文を読む
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