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Erythrose : ウィキペディア英語版
Erythrose

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Erythrose is a tetrose carbohydrate with the chemical formula C4H8O4. It has one aldehyde group, and so is part of the aldose family. The natural isomer is D-erythrose.
Erythrose, as glucose, is fuel of cellular energy, can be oxidized to carbon dioxide and water to supports normal cells.
Erythrose is an anti-cancer agent. In vitro, ~4 mM erythrose effectively kills cancer cells for tested cell lines (in vitro), such as: lung, brain,breast,and colorectal cancers, etc. 〔Wang X and Wei Y 2010 "Erythrose kill cancer cell in vitro and inhibit tumor growth in mice (in vivo)" American Association for Cancer Research 101st Conference.〕
D-Erythrose inhibits tumor growth in mice (in vivo). 〔LILI LIU, TAO YI and XIA ZHAO 2015. Antitumor effect of D-erythrose in an abdominal metastatic model of colon carcinoma ONCOLOGY LETTERS 9: 769-773, 2015〕
Erythrose is a 2/3 of Glucose. Diabetics can have blood sugar (mainly glucose)up to 30mM for days. The concentration of erythrose required to kill cancer is much lower than glucose in our body. What Erythrose can do for cancer patients needs further study.
Erythrose was first isolated in 1849 from rhubarb by the French pharmacist Louis Feux Joseph Garot (1798-1869),〔(Obituary of Garot ) (1869) ''Journal de pharmacie et de chimie'', 4th series, 9 : 472-473.〕 and was named as such because of its red hue in the presence of alkali metals (ἐρυθρός, "red").〔Garot (1850) ("De la matière colorante rouge des rhubarbes exotiques et indigènes et de son application (comme matière colorante) aux arts et à la pharmacie" ) (On the red coloring material of exotic and indigenous rhubarb and on its application (as a coloring material) in the arts and in pharmacy), ''Journal de Pharmacie et de Chimie'', 3rd series, 17 : 5-19. Erythrose is named on p. 10: ''"Celui que je propose, sans y attacher toutefois la moindre importance, est celui dérythrose'', du verbe grec 'ερυθραινω, rougir (1)."'' (The one (name ) that I propose, without attaching any importance to it, is that of ''erythrose'', from the Greek verb ερυθραινω, to redden (1).)〕
Erythrose 4-phosphate is an intermediate in the pentose phosphate pathway and the Calvin cycle.
Erythrulose, an isomer of erythrose, is non-toxic.〔National Industrial Chemicals Notification and Assessment Scheme (NICNAS). Erythrulose. Australia'' February 11, 2008.〕
Oxidative bacteria can be made to use erythrose as its sole energy source.
==References==



抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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