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Ethonam
Ethonam is an antifungal agent. ==Synthesis==
2-Aminotetralin () is alkylated with ethylchloroacetate to afford the glycine derivative. Heating with formic acid then affords the amide (2). This compound is then reacted with ethyl formate to yield hydroxymethylene ester (3). Rxn with isothiocyanic acid gives the imidazole-2-thiol (5). Desulfurization by means Raney-Nickel finishes the synthesis of ethnonam (6).
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Ethonam」の詳細全文を読む
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