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Fatty acid binding protein 7, brain (FABP7; also brain lipid binding protein, BLBP), is a human gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2173 )〕 FABP7 is expressed, during development, in radial glia by the activation of Notch receptors. Reelin was shown to induce FABP7 expression in neural progenitor cells via Notch-1 activation. According to one study, FABP7 binds DHA with the highest affinity among all of the FABPs. ==Role in pathology== FABP7 maps onto human chromosome 6q22.31, a schizophrenia linkage region corroborated by a meta-analysis. As of 2008, two studies have been conducted into FABP7 as a possible risk gene for schizophrenia,〔(Gene Overview of All Published Schizophrenia-Association Studies for FABP7 ) - SZGene database at Schizophrenia Research Forum website.〕 with one, that tested for only one SNP, showing negative and another, with seven SNPs, a positive result. The effect of the gene in the latter study was stronger in males. This study also linked FABP7 variation to weak prepulse inhibition in mice; deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「FABP7」の詳細全文を読む スポンサード リンク
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